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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177490 | 14-3-3E (YWHAE) | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR3919 【用途】WB , ICC , FC 【抗原分子量】28kDa |
质量标准: | 【产品介绍】The 14-3-3 epsilon protein (14-3-3E) is one of seven isoforms in the 14-3-3 protein family, which consists of acidic proteins expressed at high levels in neurons of the central nervous system (1). It is an adaptor protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. 14-3-3E binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif (2). It also interacts with both insulin-like growth factor I receptor (IGFIR) and insulin receptor substrate I (IRS-1), suggesting its role in the regulation of insulin sensitivity (3). 14-3-3E has also been implicated in the pathogenesis of small cell lung cancer (4).
WB, ICC, FC WB: 1:1,000 - 10,000 Human, Mouse, Rat Specificity A synthetic peptide corresponding to residues in human 14-3-3E was used as an immunogen. |
贮存: | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), |