4007787550
|
 |
||||||||||||||
| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
| JD1227177493 | 4E-BP1 (EIF4EBP1) | -- | 100ul | 0元 | 现货 | 3天 |
| 性状： | 【反应特异性】Human 【克隆 ID】Y330 【用途】WB , IHC , FC , IP 【抗原分子量】15-20kDa |
| 质量标准： | 【产品介绍】4E-BP1 (eIF4E-binding protein) also known as PHAS, is a 10-12 kDa acidic protein that compete with eIF4G for binding of eiF4E to the mRNA 5' cap structure (1). Binding of the 4E-BPs to eIF4E is reversible and is dependent on the phosphorylation status of 4E-BP. Non-phosphorylated 4E-BP1 will bind strongly to eIF4E, while the phosphorylated form will not (2). Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating 4E-BP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. However, not all phosphorylation events equally block the 4EBP1-eIF4E interaction (3-4)
WB, IHC, IP, FC WB: 1:1,000 - 10,000 Human *Cross reactivity determined by western blot only. Specificity A synthetic peptide corresponding to residues near |
| 贮存： | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), |
