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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177517 | Akt1/PKBa (C-term) | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human , Mouse , Rat 【克隆 ID】Y89 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】59 kDa |
质量标准: | 【产品介绍】Akt1/PKBa is a Ser/Thr protein kinase whose kinase activity plays a key role in various cellular functions, including apoptosis, glycogen synthesis, a n d cell growth . Akt1/PKBa is activated by various growth a n d survival fact o r s (1). Phosph o r ylation on Thr308, Ser473 a n d Tyr474 is required f o r full activity. Akt1/PKBa inhibits apoptosis by phosph o r ylating a n d inactivating several targets, including caspase-9 (2). Akt1/PKBa regulates glycogen synthesis by phosph o r ylating a n d inactivating glycogen synthase kinase-3a a n d b (3,4). Three mammalian Akt1/PKBa isof o r ms have been identified.
A. Western blot analysis on MCF-7 cell lysate using |