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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177525 | Alpha-fetoprotein (C-term) | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human , Rat 【克隆 ID】Polyclonal 【用途】WB , IHC 【抗原分子量】70 kDa. |
质量标准: | 【产品介绍】Alpha-fetoprotein (AFP) is a serum glycoprotein protein produced in the liver o r yolk sac of fetal staged mammals. AFP synthesis is minimal after birth a n d trace amount is expressed in the adult liver (1). AFP gene expression is regulated by the interactions between steroid h o r mone recept o r s a n d transcriptional fact o r s in separate signal transduction pathways (2). AFP functions as a binding a n d transp o r ting lig a n d a n d cell growth regulat o r . Elevated expression level of AFP has been implicated in col o r ectal, ovarian, pancreatic, testicular, a n d certain liver cancers. High level of AFP is also seen some diseases, such as hepatitis a n d colitis. AFP is used as a screening marker f o r fetal abn o r malities in pregnant women, such as Down syndrome. Recently, AFP has been introduced as an anti-cancer drug-lig a n d carrier, transp o r ting drugs to target tum o r cells, increasing anti-tum o r efficiency (3).
A. Western blot analysis on HepG2 cell lysate of |