Alpha-Synuclein Phospho (pY125) (SNCA)

人 ELISA 大鼠ELISA 小鼠ELISA 兔 ELISA 豚鼠ELISA 羊ELISA 猪ELISA 狗ELISA 猴ELISA 鸡ELISA 牛ELISA 农残快速检测系列化学污染物检测试剂盒调味品检测试剂盒非食用色素检测试剂蔬果检测试剂盒副食品检测试剂盒酒类检测试剂盒甜味剂检测试剂盒防腐剂检测试剂盒蜂蜜检测试剂盒面粉质量检测试剂盒肉类检测试剂盒食用油检测试剂盒鲜奶质量检测试剂盒 β兴奋胶体金系列水产药物残留胶体金系列水质快速检测盒系列奶类药物残留胶体金系列蜂蜜药物残留胶体金系列真菌霉毒素胶体金系列化肥质量检测试剂盒化妆品检测试剂盒保健品非法添加筛查试剂盒瘦肉精系列兽药残留系列抗生素系列真菌毒素系列猪病检测系列家禽检测系列牛羊系列家宠系列诊断试剂盒

抗体产品

一抗二抗干细胞相关抗体标签抗体内参抗体食品安全检测类抗体

蛋白质组化

蛋白提取蛋白纯化蛋白定量蛋白电泳免疫印迹

分子生物试剂及试剂盒

PCR及RT-PCR 核酸分离与纯化细胞及检测基因克隆与表达核酸电泳克隆及表达

植物提取物

茶叶提取类丹参提取类银杏提取类天然活性单体成分标准化植物提取类比例化植物提取类中药提取其他提取多糖系列提取物

首页》生化科研试剂》抗体产品》一抗

Alpha-Synuclein Phospho (pY125) (SNCA)

Rabbit Monoclonal Antibody

别名：	SNCA antibody, MGC110988 antibody, NACP antibody, PARK1 antibody, PARK4 antibody, PD1 antibody, Alpha-synuclein antibody, Non-A beta component of AD amyloid antibody, Non-A4 component of amyloid precursor antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177526	Alpha-Synuclein Phospho (pY125) (SNCA)	--	100ul	3500元	咨询客服	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human
【克隆 ID】EPR2179(2)
【用途】WB , ICC
【抗原分子量】18kDa

质量标准：

【产品介绍】Alpha-Synuclein is expressed predominantly
in brain, where it is concentrated in presynaptic
nerve terminals (1). The deposition of the
abundant presynaptic brain protein alpha-synuclein
as fibrillary aggregates in neurons or glial cells is
a hallmark lesion in a subset of neurodegenerative disorders. These disorders include Parkinson's
disease (PD), dementia with Lewy bodies (DLB) and
multiple system atrophy, collectively referred to as synucleinopathies. Phosphorylation of alpha-synuclein at
Ser 129 promoted fibril formation in vitro and these
results highlight the importance of phosphorylation
of filamentous proteins in the pathogenesis of neurodegenerative disorders (2). Parkinson's disease (PD)
is a common neurodegenerative disorder characterized by
the progressive accumulation in selected neurons of
protein inclusions containing alpha-synuclein and
ubiquitin. It is hypothesized that parkin and
alpha-synculein interact functionally, namely, that
parkin ubiquitinates alpha-synuclein normally and that
this process is altered in autosomal recessive PD (3).

Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:100 - 250
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis.

Products Data
Western blot analysis on HeLa cell lysates
using anti-Phospho-Alpha-Synuclein (pY125)
RabMAb (cat. #3932-1). Cells were either (A)
untreated (B) treated with pervanadate.

Specificity

A phospho specific peptide corresponding to
residues surrounding tyrosine 125 of human
Alpha-Synuclein was used as an immunogen. This antibody
only detects Alpha-Synuclein phosphorylated at tyrosine 125.

贮存：

Storage Condition and Buffer

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt