4007787550
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| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
| JD1227177527 | Alpha-Tubulin | -- | 100ul | 0元 | 现货 | 3天 |
| 性状： | 【反应特异性】Human , Mouse , Rat 【克隆 ID】EP1332Y 【用途】WB , IHC , ICC , IP 【抗原分子量】50 kDa |
| 质量标准： | 【产品介绍】Microtubules are essential parts in eukaryotic cell structures, transp o r tation, a n d mitosis. It consists mainly of 2 soluble protein subunits, alpha a n d beta tubulin. Beta tubulin binds to alpha tubulin to f o r m tubulin heterodimer which is post-translationally modified (1). The tubulin dimer complex binds to GTP a n d assembles onto the positive ends of microtubules. After inc o r p o r ation into the microtubules, bound GTP is hydrolyzed by beta tubulin. The stability of the dimer in the microtubules is depended on presence of beta tubulin, where dimer with GTP bound beta-tubulin is stable to microtubule inc o r p o r ation (2). F o r both type of tubulin, the carboxy-terminal tail is pos-translationally modified to regulate associated protein binding at microtubule surface (3). A mutation on alpha tubulin has been linked to abn o r mal neuronal migration a n d neurodevelopmental dis o r ders in human (4).
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