Apolipoprotein E (N-term) (APOE)_珈得尔化学试剂

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Apolipoprotein E (N-term) (APOE)

Rabbit Monoclonal Antibody

别名：	APOE antibody, AD2 antibody, LDLCQ5 antibody, LPG antibody, MGC1571 antibody, Apolipoprotein E antibody, antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177535	Apolipoprotein E (N-term) (APOE)	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human
【克隆 ID】EP1373Y
【用途】WB , IHC , FC , IP
【抗原分子量】36kDa

质量标准：

【产品介绍】The apolipoproteins are family of
amphipathic lipoproteins that plays a crucial role in
lipid metabolism. In particular, apolipoprotein E (apo E)
is a major component of high density lipoproteins
(HDL) chylomicrons and very low-density lipoprotein
(VLDL), which functions to remove excess cholesterol.
Apo E mediates lipid metabolism and cholesterol
homeostasis by binding to several hepatic
lipoprotein receptors, such as low density
lipoprotein receptor (LDLR) and the LDLR-related
protein (1). Apo E deficiency is linked
to hyperlipoproteinemia type III; a genetic
disorder characterized by elevated plasma cholesterol
and triglyceride levels and accelerated coronary
artery disease (2). Three major isoforms of Apo E
(E2, E3, E4) has been identified, with E3 being the
most common in human. E4 presence has been associated
to increase probability of developing late-onset form
of Alzheimer disease (3).

Recommended Applications

WB, IHC, IP, FC
Applications and Recommended Dilution Factors

WB: 1:500 - 1000
IHC: 1:100 - 1:250
IP: 1:70
FC: 1:30
Species Reactivity *

Human

*Cross reactivity determined by western blot only.

Products Data
A. Western blot analysis on human serum using anti-Apo
E RabMAb. (Cat. # 1981-1).

B. Immunohistochemical analysis of paraffin-embedded
human fetal liver using anti-Apo E RabMAb (cat. # 1981-1).

Specificity

A synthetic peptide corresponding to residues near
the N-term of human apolipoprotein E was used as an immunogen.

贮存：

Storage Condition and Buffer

Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.