B7-H2 (ICOSLG)_珈得尔化学试剂

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B7-H2 (ICOSLG)

Rabbit Monoclonal Antibody

别名：	ICOSLG antibody, B7-H2 antibody, B7H2 antibody, B7RP-1 antibody, B7RP1 antibody, CD275 antibody, GL50 antibody, ICOS-L antibody, ICOSL antibody, KIAA0653 antibody, LICOS antibody, ICOS ligand antibody, B7-like protein Gl50 antibody, B7-related protein 1 a
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177551	B7-H2 (ICOSLG)	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human
【克隆 ID】EPR6071
【用途】WB , ICC
【抗原分子量】63 - 72kDa

质量标准：

【产品介绍】B7-H2, or Inducible costimulator ligand
(ICOSL), is a member of the Ig superfamily and belongs
to the B7 family of costimulatory molecules. It
specifically binds to ICOS, but not to other T
cell costimulatory molecules such as CD28 and
CTLA-4. B7-H2-ICOS interaction appears to be very
important in the expansion of activated T cells
and late-phase immune responses (1). B7-H2 enhances
the proliferation of both CD4 and CD8 T cells, the
secretion of Th1- and/or Th2-type cytokines, and
the expression of CD154 (CD40 ligand) on T cells (2). It
is expressed constitutively on B lymphocytes and at
low levels on monocytes (3). Furthermore,
B7-H2-ICOS interaction induces IL-10 production, which
plays an important role in reducing immune responses (4).

Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:50 - 100
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis.

Products Data
Western blot analysis on (A) HL-60, (B) HuT78, (C)
HUVEC treated with TNF-alpha, and (D) HUVEC cell
lysates using anti-B7-H2 RabMAb (cat. #5329-1).

Specificity

A synthetic peptide corresponding to residues in
the intracellular domain of human B7-H2 was used as
an immunogen.

贮存：

Storage Condition and Buffer

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt