Bag-2 (BAG2)_珈得尔化学试剂

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Bag-2 (BAG2)

Rabbit Monoclonal Antibody

别名：	BAG2 antibody, BAG-2 antibody, KIAA0576 antibody, MGC149462 antibody, dJ417I1.2 antibody, BAG family molecular chaperone regulator 2 antibody, Bcl-2-associated athanogene 2 antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177555	Bag-2 (BAG2)	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR3568
【用途】WB , ICC
【抗原分子量】23kDa

质量标准：

【产品介绍】BAG-2 is a member of a family of
BAG-related proteins (BAG-2, BAG-3, BAG-4,
BAG-5). BAG-family proteins may play a role in
providing opportunities for specification
and diversification of Heat Shock Protein (Hsp70)
chaperone functions. Hsp70 family molecular chaperones
play critical roles in protein folding and trafficking
in all eukaryotic cells. BAG-1 binds the ATPase domains
of Hsp70 and Hsc70, modulating their chaperone activity
and functioning as a competitive antagonist of
the co-chaperone Hip. BAG-2 proteins bind with high
affinity to the ATPase domain of Hsc70 and inhibit
its chaperone activity in a Hip-repressible manner (1).

Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:1000 - 2000
ICC: 1:100 - 250
Species Reactivity *

Human, Mouse, Rat

*Cross reactivity determined by western blot only.

Products Data
A. Western blot analysis on (A) Jurkat (B) HeLa and (C)
A549 cell lysate using anti-Bag2 RabMAb
(cat. # 2622-1), dilution 1:2000.

B. Immunofluorescent staining of HeLa cells using
anti-BAG2 RabMAb (cat. #2622-1).

Specificity

A synthetic peptide corresponding to residues in
the C-terminus of human Bag-2 was used as immunogen.

贮存：

Storage Condition and Buffer

Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.