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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177560 | Bcl-2 Rabbit Antibody | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human , Mouse 【克隆 ID】E17 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】26 kDa |
质量标准: | 【产品介绍】The Bcl-2 family of proteins regulate apoptosis by controlling mitochondrial permeability a n d release of cytochrome c. Bcl-2 is an anti-apoptotic protein that resides in the outer mitochondrial wall a n d inhibits release of cytochrome c (1). Over-expression of Bcl-2 has been shown to promote cell survival by suppressing apoptosis. It has been documented that bcl-2 becomes deregulated in tum o r cells as a result of translocation into the immunoglobulin heavy-chain locus a n d is theref o r e activated in B cell malignancies (2). It has also been shown that post-translational modification of Bcl-2, phosph o r ylation at serine 70, may be required to render its full a n d / o r enhanced anti-apoptotic effect (3, 4).
A. Western blot analysis of Jurkat cell lysate B. Immunohistochemical analysis of paraffin-embedded C. Flow cytometric analysis of permeabilized Jurkat |