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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177572 | Bid Rabbit Antibody | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human 【克隆 ID】Y8 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】22 kDa |
质量标准: | 【产品介绍】Bid, BH3 interacting domain death agonist, is a pro-apoptotic member of the Bcl-2 family of proteins that regulate apotosis. Bid is localized to the cytosol in an inactive precurs o r f o r m. Upon caspase-8 binding in the Fas signaling pathway, Bid is cleaved a n d the active Bid fragment translocates to mitochondria a n d induces cytochrome c release a n d the resulting apoptotic cascade (1-3). Bid contains a BH3 domain which allows it to dimerize with a n d counter the death repress o r effects of Bcl-2. BID has also been shown to heterodimerize with Bcl-x a n d the death agonist Bax (4).
B. Immunohistochemical analysis of paraffin-embedded |