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| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
| JD1227177574 | BLNK Rabbit Antibody | -- | 100ul | 0元 | 现货 | 3天 |
| 性状： | 【反应特异性】Human , Mouse 【克隆 ID】Y491 【用途】WB , IHC , IP 【抗原分子量】68/70 kDa |
| 质量标准： | 【产品介绍】B-cell linker protein (BLNK, also known as SLP65, BASH, a n d BCA) is a B cell adapt o r that plays an imp o r tant role in B cell development a n d in BCR-signal transduction. Since BLNK does not encode any intrinsic enzymatic activity, its function is to serve as a scaffold f o r assembling macromolecular complexes which includes enzymes (PLC gamma, Vav a n d Btk) a n d additional linker proteins (Grb2 a n d Nck) (1-3) . In addition, BLNK binds Btk a n d is required f o r activation of the transcription fact o r NF-κB. Tyrosine phosph o r ylation of BLNK by Syk provides specific docking sites f o r these SH2-containing effect o r proteins which in turn permits phosph o r ylation a n d / o r activation of their respective signaling pathways.
A. Western blot analysis on Raji cell lysate using B. Immunohistochemical analysis of paraffin-embedded |
