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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177577 | B-Raf Phospho (pS729) (BRAF) | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR2207 【用途】WB , IHC 【抗原分子量】94kDa |
质量标准: | 【产品介绍】B-Raf, also know as c-Rmil, is a Serine/Threonine protein kinase member of the Raf family which includes Raf-1 and A-Raf. B-Raf is involved in the transduction of mitogenic signals from the cell membrane to the nucleus (1). Composed of three conserved region (CR1, CR2, CR3) B-Raf is expressed primarily in the brain and in the nervous system (2). It has been observed that MAPK is activated by B-Raf in response to nerve growth factor (3). More than 60% of malignant melanomas were found to contain a specific mutation, B-Raf (V599E) the product of which possesses constitutive kinase activity (4). Mutations in B-Raf have also been identified in lung cancer and non-Hodgkin lymphoma.
WB, IHC WB: 1:1,000 - 10,000 Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Specificity A phospho specific peptide corresponding to |
贮存: | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, |