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| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
| JD1227177578 | B-Raf Phospho (pT401) | -- | 100ul | 0元 | 现货 | 3天 |
| 性状： | 【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR2208Y 【用途】WB , IP 【抗原分子量】94 kDa |
| 质量标准： | 【产品介绍】B-Raf, also know as c-Rmil, is a Serine/Threonine protein kinase member of the Raf family which includes Raf-1 a n d A-Raf. B-Raf is involved in the transduction of mitogenic signals from the cell membrane to the nucleus (1). Composed of three conserved region (CR1, CR2, CR3) B-Raf is expressed primarily in the brain a n d in the nervous system (2). It has been observed that MAPK is activated by B-Raf in response to nerve growth fact o r (3). M o r e than 60% of malignant melanomas were found to contain a specific mutation, B-Raf (V599E) the product of which possesses constitutive kinase activity (4). Mutations in B-Raf have also been identified in lung cancer a n d non-Hodgkin lymphoma.
A. Western blot analysis on PC-12 cell lysates |
