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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177627 | CD44 Rabbit Antibody | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human 【克隆 ID】EPR1013Y 【用途】WB , IHC , ICC , FC 【抗原分子量】85-90 kDa |
质量标准: | 【产品介绍】CD44 is a cell-surface glycoprotein postulated to play a role in a variety of biological processes, including lymphocyte homing a n d tum o r -cell metastasis. Several isof o r ms of CD44 have been identified in human cells, a n d the genesis of some of these isof o r ms has been attributed to alternative splicing. Underst a n d ing of mechanisms regulating CD44 alternative splicing may provide insights into diverse processes, including tum o r -cell metastasis a n d lymphocyte homing (1). The deduced protein sequence of 699 amino acids has a novel 339 amino acid domain i n s e r t ed into the proximal extracellular domain of the st a n d ard, leukocyte f o r m of CD44. The additional domain adds a number of potential N- a n d O-linked glycosylation sites a n d two proteolysis sites to this f o r m of CD44 (2). CD44 is defined as a structurally diverse, but immunologically related, set of intrinsic membrane macromolecules, a n d suggests that these structurally varied f o r ms might be expected to manifest multiple functions (3)
B. Immunohistochemical staining of paraffin-embedded |