Cripto 1 / 3 (TDGF1)_珈得尔化学试剂

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Cripto 1 / 3 (TDGF1)

Rabbit Monoclonal Antibody

别名：	TDGF1 antibody, CR antibody, CRGF antibody, CRIPTO antibody, Teratocarcinoma-derived growth factor 1 antibody, Epidermal growth factor-like cripto protein CR1 antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177666	Cripto 1 / 3 (TDGF1)	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human , Mouse
【克隆 ID】EPNCI106B
【用途】WB , IP
【抗原分子量】21kDa

质量标准：

【产品介绍】Cripto 1, also known as Teratocarcinoma-
derived growth factor 1 (TDGF1), is a member of the
EGF-CFC family that is required for proper
laterality development in humans (1, 2). It is an
obligate coreceptor involved in the NODAL ligand
signaling pathway, a developmental program implicated
in midline, forebrain, and left-right axis development
(2). Thus, Cripto 1 could play a role in the
determination of the epiblastic cells that subsequently
give rise to the mesoderm (1). It also increases
migration of cells in vitro (3). Cripto 1 is expressed
in embryonic stem (ES) cells and during the early phases
of embryo development (4). Furthermore, it is expressed
at high levels in the majority of different types of
human carcinomas including breast, colon, and lung (5).

Recommended Applications

WB, IP
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IP: 1:10 - 100
Species Reactivity *

Human, Mouse

*Species cross-reactivity is based on WB analysis.

Products Data
Western blot analysis on (A) NCCIT and (B) F9 cell
lysates using anti-Cripto 1 / 3 RabMAb (cat. #5108-1).

Specificity

A synthetic peptide corresponding to residues in
human Cripto 1 was used as an immunogen. This antibody
cross-reacts with Cripto 3.

This antibody was developed as part of a
collaboration between Epitomics, the National
Cancer Institute's Center for Cancer Research and the lab
of David Solomon.

贮存：

Storage Condition and Buffer

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt