CSTB antibody_珈得尔化学试剂

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CSTB antibody

Rabbit Monoclonal Antibody

别名：	Cystatin B (CSTB), CST6 antibody, EPM1 antibody, PME antibody, STFB antibody, Cystatin-B antibody, CPI-B antibody, Liver thiol proteinase inhibitor antibody, Stefin-B antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177678	CSTB antibody	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human , Rat
【克隆 ID】EPR3931
【用途】WB , IHC , FC
【抗原分子量】11kDa

质量标准：

【产品介绍】Cystatin B is a member of the cysteine
protease inhibitor superfamily, functioning as
an intracellular thiol protease inhibitor (1). It plays
a role in protecting proteinases from lysosomal leakage
(1, 2). The second hairpin loop and the C-terminal end
of Cystatin B anchor the inhibitor to target
proteinases (3). Cystatin B interacts with and
inhibits proteases of the cathepsin family (4). A
deficiency in cystatin B is observed in
progressive myoclonic epilepsy type 1 (1). This
deficiency predisposes neurons to oxidative stress
that leads to neuronal death and degeneration (1).
In addition, Cystatin B has been linked to amyloid
fibril formation in vitro and is overexpressed
in hepatocellular carcinoma (5, 6).

Recommended Applications

WB, IHC, FC
Applications and Recommended Dilution Factors

WB: 1:1,000-10,000
IHC: 1:100 - 250
FC: 1:10 - 100
Species Reactivity

Human, Rat

Products Data

Western blot analysis on (A) U87-MG, (B) JAR, and (C)
human bladder cell lysates using anti-Cystatin B
RabMAb (cat. # 2821-1).

Immunohistochemical analysis of paraffin-embedded
human colon tissue using anti-Cystatin B RabMAb
(cat. #2821-1).

Immunohistochemical analysis of paraffin-embedded
human kidney tissue using anti-Cystatin B RabMAb
(cat. #2821-1).

Specificity

A synthetic peptide corresponding to residues in
human Cystatin B was used as an immunogen.

贮存：

Storage Condition and Buffer

Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.