4007787550
|
 |
||||||||||||||
| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
| JD1227177685 | Cytokeratin 16 (KRT16) | -- | 100ul | 0元 | 现货 | 3天 |
| 性状： | 【反应特异性】Human 【克隆 ID】EP1615Y 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】48kDa |
| 质量标准： | 【产品介绍】The human type I keratin 16 (CK16) is constitutively expressed in a number of complex epithelial tissues, including skin, but is better known for its induction under conditions favoring enhanced proliferation or abnormal differentiation, including wound healing, psoriasis, and cancer (1). CK16 is expressed in suprabasal interfollicular epidermis in wound healing and other pathological conditions associated with hyperproliferation, such as psoriasis and are induced when keratinocytes are cultured in vitro. However, CK16 is also constitutively expressed in normal suprabasal mucosal and palmoplantar keratinocytes (2). Pachyonychia congenita (PC) is a group of inherited ectodermal dysplasias, the characteristic phenotype being hypertrophic nail dystrophy. The PC-1 phenotype may be distinguished by the absence of the epidermal cysts found in PC-2, and it has been shown to be caused by mutations in either keratin K16 or its expression partner, the K6a isoform of K6. Mutations in K16 have also been shown to cause a milder related phenotype, focal non-epidermolytic palmoplantar keratoderma (3).
WB, IHC, ICC, IP, FC WB: 1:2000 - 10,000 Human *Cross reactivity determined by western blot only. Products Data B. Immunohistochemical analysis of paraffin-embedded Specificity A synthetic peptide corresponding to residues near |
| 贮存： | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), |
