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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177699 | DAP12 (TYROBP) | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human 【克隆 ID】EPR5173 【用途】WB , ICC 【抗原分子量】12kDa |
质量标准: | 【产品介绍】DAP12 is a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. It may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. DAP12 may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this protein have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL (1).
WB, ICC WB: 1:1,000 - 10,000 Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) peripheral blood Specificity A synthetic peptide corresponding to residues in human |
贮存: | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, |