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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177701 | DAPK3 | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human 【克隆 ID】EPR1636Y 【用途】WB , FC 【抗原分子量】52 kDa |
质量标准: | 【产品介绍】Death-associated protein kinase (DAPK3), which is a mediat o r of apoptosis, is induced by gamma interferon. DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities (1). Results suggest that DAPK3, in collab o r ation with Daxx a n d Par-4, mediates a novel nuclear pathway f o r apoptosis (2). It has been shown that the nuclear serine/threonine-specific kinase phosph o r ylates c o r e histones H3 a n d H4, a n d myosine light chain in vitro. HeLa ZIPK phosph o r ylated the regulat o r y light chain of myosin II (MRLC) at both serine 19 a n d threonine 18 in a Ca2+/calmodulin independent manner. It interacts with transcription a n d splicing fact o r s as well as with pro-apoptotic protein Par-4 suggesting that it participates in multiple cellular processes (3).
A. Western blot analysis on HeLa cell lysate |