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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177708 | DDIT4 / REDD-1 | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR4037(2) 【用途】WB , ICC 【抗原分子量】35kDa |
质量标准: | 【产品介绍】DDIT4 / REDD-1 is a transcriptional target of p53 induced following DNA damage. It functions in the regulation of reactive oxygen species (ROS), which is involved in p63-mediated regulation of epithelial differentiation (1). DDIT4 / REDD-1 inhibits mTOR kinase activity in non-muscle and muscle cells downstream of Akt/PKB and upstream of TSC2. As a stress responsive negative regulator of mTOR signaling, it is implicated in controlling skeletal muscle size (2). Studies show either a pro- or an anti-apoptotic role during the stress response, depending on the cell context (3). Furthermore, DDIT4 / REDD-1 is essential for hypoxia regulation of TORC1 activity (4).
WB, ICC WB: 1:1,000 - 10,000 Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) Jurkat, (B) 293T, and Specificity A synthetic peptide corresponding to residues in human |
贮存: | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, |