DLC8 (N-term)_珈得尔化学试剂

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蛋白提取蛋白纯化蛋白定量蛋白电泳免疫印迹

分子生物试剂及试剂盒

PCR及RT-PCR 核酸分离与纯化细胞及检测基因克隆与表达核酸电泳克隆及表达

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DLC8 (N-term)

Rabbit Monoclonal IgG

别名：	Dynein light chain LC8-type 1, 8 kDa dynein light chain, DLC8, Protein inhibit o r of neuronal nitric oxide synthase, PIN
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177714	DLC8 (N-term)	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human , Mouse , Rat
【克隆 ID】EP1660Y
【用途】WB , IHC , ICC , IP
【抗原分子量】10 kDa

质量标准：

【产品介绍】DLC8 protein bound efficiently to gephyrin in
in vitro binding assays a n d colocalized with
gephyrin during coexpression in HEK293 cells. The
binding site f o r DLC8 was mapped to a fragment of 63
amino acids within the central linker domain of gephyrin.
In hippocampal neurons, endogenous DLC8 protein was
enriched at synaptic sites identified by synaptophysin
a n d gephyrin immunostaining. Because DLC8 has
been described as stoichiometric components of
cytoplasmic dynein a n d myosin-Va complexes,
results suggest that mot o r proteins are involved in
the subcellular localization of gephyrin (1). DLC8
was identified as a transp o r t molecule in the
cytoplasm. DLC8 co-localizes with TRPS1 in
dot-like structures in the cell nucleus. In an electroph
o r etic mobility shift assay it was shown that
the interaction of DLC8 a n d TRPS1 lowers the binding
of TRPS1 to the GATA consensus sequence. In addition DLC8
is able to suppress the transcriptional repression
activity of TRPS1 (2).

WB: 1:10,000
IHC: 1:100 250
ICC: 1:100 250
IP: 1:100

A. Western blot analysis on HeLa cell lysate using
anti-DLC8 RabMAb (cat. # 2003-1), dilution 1:10,000.

B. Immunohistochemical staining of paraffin-embedded
human liver using anti-DLC8 RabMAb (cat. #2003-1).