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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177717 | DNA-PK / PRKDC | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human 【克隆 ID】EPR392 【用途】WB , ICC 【抗原分子量】460kDa |
质量标准: | 【产品介绍】DNA-activated serine/threonine protein kinase (DNA-PK) is a nuclear protein kinase that is involved in DNA nonhomologous end joining (NHEJ) required for double- strand brake repair and V(D)J recombination. DNA-PK is composed of a large catalytic subunit of ~470 kDa (DNA-PKcs) and a DNA binding heterodimer of approximately 70- and 80-kDa subunits called Ku. (1-2). Autophosphorylation of DNA-PK correlates with loss of protein kinase activity and dissociation of the DNA-PKcs-Ku complex. DNA-PK phosphorylates Hsp90, p53 and c-Jun (3-4).
WB, ICC WB: 1:1,000 - 10,000 Human *Species cross-reactivity is based on WB analysis Products Data Western blot analysis on (A) K562, (B) Molt-4, Specificity A synthetic peptide corresponding to residues in |
贮存: | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, |