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| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
| JD1227177744 | EGFR Phospho (pT678) | -- | 100ul | 0元 | 现货 | 3天 |
| 性状： | 【反应特异性】Human 【克隆 ID】EP2255Y 【用途】WB , ICC 【抗原分子量】175kDa |
| 质量标准： | 【产品介绍】Epidermal growth factor receptor (EGFR) is a 175 kDa transmembrane glycoprotein receptor tyrosine kinase that, activated by epidermal growth factor (EGF), affects cell growth and differentiation (1). Binding of EGF or TGF alpha to EGFR activates tyrosine kinase activity of the receptor (2). The epidermal growth factor (EGF) receptor is regulated by EGF-stimulated autophosphorylation and by phorbol ester-stimulated, protein kinase C (Ca2+/ phospholipid-dependent enzyme) mediated phosphorylation at identified sites. The EGF receptor contains additional phosphorylation sites including a prominent phosphothreonine and several phosphoserines which account for the majority of phosphate covalently bound to the receptor in vivo. Analysis of predicted secondary structure of the EGF receptor reveals that all of the phosphorylation sites are located near beta turns (3).
WB, ICC WB: 1:1,000 - 10,000 Human *Cross reactivity determined by western blot only. Products Data B. Immunofluorescent staining of A431 cells Specificity A phospho specific peptide corresponding to |
| 贮存： | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
