4007787550
|
 |
||||||||||||||
| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
| JD1227177787 | FE65 (APBB1) | -- | 100ul | 0元 | 现货 | 3天 |
| 性状： | 【反应特异性】Human 【克隆 ID】EPR3538 【用途】WB , IHC , ICC 【抗原分子量】100kDa |
| 质量标准： | 【产品介绍】Amyloid beta A4 precursor protein-binding family B member 1 (FE65) is a member of a family of multidomain adaptor proteins (FE65, FE65L1, and FE65L2) that form multiprotein complexes with a range of functions. FE65 is highly expressed in the brain and it has three protein-protein interaction domains: a WW domain and two PID/PTB domains. Through the PTB2 domain, FE65 interacts with the Alzheimer’s disease amyloid precursor protein (APP) intracellular domain (AICD) and can alter APP processing. The WW domain is responsible for the interaction with various proteins, which in turn interacts with the cytoskeleton. The second PID/PTB domain of FE65 binds to the transcription factor, CP2/LSF/LBP1 protein (1, 2). FE65 also plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis (3).
WB, IHC, ICC WB: 1:1,000 - 10,000 Human Products Data Specificity A synthetic peptide corresponding to residues in human |
| 贮存： | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), |
