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| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
| JD1227177798 | FKBP4 | -- | 100ul | 0元 | 现货 | 3天 |
| 性状： | 【反应特异性】Human 【克隆 ID】EPR6619 【用途】WB , IHC , FC , IP 【抗原分子量】52kDa |
| 质量标准： | 【产品介绍】FKBP4 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. FKBP4 interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. It is known to associate with phytanoyl-CoA alpha-hydroxylase, and it can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. FKBP4 correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy (1).
WB, IHC, IP, FC WB: 1:50,000 - 200,000 Human *Species cross-reactivity is based on WB analysis. Products Data Immunohistochemical analysis of paraffin-embedded Specificity A synthetic peptide corresponding to residues near |
| 贮存： | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, |
