FOXO4 Phospho (pS262)_珈得尔化学试剂

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FOXO4 Phospho (pS262)

Rabbit Monoclonal Antibody

别名：	FOXO4 antibody, AFX antibody, AFX1 antibody, MGC120490 antibody, MLLT7 antibody, Forkhead box protein O4 antibody, Fork head domain transcription factor AFX1 antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177807	FOXO4 Phospho (pS262)	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human
【克隆 ID】EPR2315(2)
【用途】WB
【抗原分子量】65kDa

质量标准：

【产品介绍】FOXO4 is a member of the O class of
winged helix/forkhead transcription factor family. It
is regulated by factors involved in growth
and differentiation indicating they play a role in
these processes. A translocation involving this protein
on chromosome X and the homolog of the Drosophila
trithorax gene, encoding a DNA binding protein, located
on chromosome 11 is associated with leukemia (1).
A constitutively active FOXO4 mutant where
phosphorylation sites Thr-32, Ser-187 and Ser-262 have
been mutated to alanine may have therapeutic potential
in ERBB2/HER2-overexpressing cancers as it inhibits
ERBB2-mediated cell survival, transformation
and tumorigenicity (2).

Recommended Applications

WB
Applications and Recommended Dilution Factors

WB: 1:10,000 - 50,000
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on 293T cell lysates
using anti-Phospho-FOXO4 (pS262) RabMAb (cat. #5453-1).
Lane A: FOXO4 transfected 293T, Lane B: FOXO4
transfected 293T treated with Alkaline Phosphatase, and
Lane C: 293T.

Specificity

A phospho specific peptide corresponding to
residues surrounding serine 262 of human FOXO4 was used
as an immunogen. This antibody only detects
FOXO4 phosphorylated at serine 262.

贮存：

Storage Condition and Buffer

Store at -20° C. Buffer: PBS (pH 7.2), 0.01% sodium
azide, 50% Glycerol and 0.05% BSA. Stable for 12 months
from date of receipt.