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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227177822 | Gab2 Rabbit Antibody | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【反应特异性】Human , Mouse , Rat 【克隆 ID】EP369Y 【用途】WB , ICC , FC , IP 【抗原分子量】97 kDa |
质量标准: | 【产品介绍】Gab2 (Grb2-associated binder-2) is an adapt o r protein involved in numerous intracellular signaling pathways via its interaction with recept o r tyrosine kinases (RTKs), growth fact o r s a n d cytokines. Gab2 is a substrate of various RTKs, including EGFR, insulin recept o r , cytokine recept o r s as well as B a n d T cell antigen recept o r s; Gab2 acts as a docking protein f o r several SH2-containing proteins (1-3). Upon tyrosine phosph o r ylation, Gab2 interacts with SHP2 tyrosine phosphatase a n d GRB2 adapt o r protein PI3-kinase, CrkL a n d SHC (4-5).
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