4007787550
|
 |
||||||||||||||
| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
| JD1227177831 | Gelsolin Rabbit Antibody | -- | 100ul | 0元 | 现货 | 3天 |
| 性状： | 【反应特异性】Human 【克隆 ID】EP1940Y 【用途】WB , IHC 【抗原分子量】90 kDa |
| 质量标准： | 【产品介绍】Gelsolin is a large a n d complex actin-binding protein that belongs to actin-severing gelsolin/villin super family. Gelsolin is a regulat o r of actin filament assembly a n d disassembly a n d consists of six homologous subdomains (S1-S6). When C-terminal tail (S6) is bound to calcium ion, it straightens a n d exposes actin binding sites located on S2s helices, leading to Gelsolin actin-serving activity (1). Gelsolin is inhibited by phosphatidylinositol (4,5)-bisphosphate (PIP2), where PIP2 will bind to S1, S2, a n d S3 sites. Gelsolin is involved in podosome f o r mation a n d has been linked to inhibition of apoptosis by preventing release of cytochrome C (2).
B. Immunohistochemical analysis of paraffin-embedded |
