GNB2_珈得尔化学试剂

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PCR及RT-PCR 核酸分离与纯化细胞及检测基因克隆与表达核酸电泳克隆及表达

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GNB2

Rabbit Monoclonal Antibody

别名：	GNB2 antibody, - antibody, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 antibody, G protein subunit beta-2 antibody, Transducin beta chain 2 antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227177841	GNB2	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR3261Y
【用途】WB , ICC
【抗原分子量】35kDa

质量标准：

【产品介绍】Guanine nucleotide binding protein beta-2
(GNB2) is a G-protein subunit belonging to WD repeat
G protein beta family. GNB2 functions as a modulator
or transducer for trans-membrane signaling pathway
systems. G-protein is composed of alpha, beta, and
gamma subunits, where beta and gamma subunits are
required for GTPase activity and G-protein
effector interaction (1). Specifically, GNB2 interacts
with the glucocorticoid and migrates into the nucleus
to suppress GR-induced trans-activation of
the glucocorticoid-responsive genes (2). GNB2 has
been identified as a binding partner to Ataxin 10,
an important target in SCA10 disorder, and also a partner
in regulating NTE, a protein known to cause
delayed neuropathy with degeneration of nerve axon (3, 4).

Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:100 - 250
Species Reactivity *

Human, Mouse, Rat

*Cross reactivity determined by western blot only.

Products Data

A. Western blot analysis on A) SH-SY5Y, B) Jurkat,
and C) NIH3T3 lysates using anti-GNB2 RabMAb (cat. #2515-1).

Specificity

A peptide corresponding to residues near N-term of
human GNB2 was used as an immunogen.

贮存：

Storage Condition and Buffer

Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.