Alpha-Actinin 2_珈得尔化学试剂

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Alpha-Actinin 2

别名：	ACTN2, Alpha-actinin-2, Alpha-actinin skeletal muscle isoform 2;F-actin cross-linking protein
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227178918	Alpha-Actinin 2	--	100ul	3575元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【产品类型】Rabbit Monoclonal IgG
【反应特异性】Human , Mouse , Rat
【克隆 ID】EP2530Y
【用途】WB , IHC , IP
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】100 kDa

质量标准：

【产品介绍】Alpha-actinin is a ubiquitously
expressed protein found in numerous actin structures.
It consists of an N-terminal actin binding domain, a
central rod domain, a n d a C-terminal domain
a n d functions as a homodimer to cross-link
actin filaments. The rod domain determines the
distance between cross-linked actin filaments a n d
also serves as an interaction site f o r
several cytoskeletal a n d signaling proteins (1).
Alpha-actinins are a multigene family of four
actin-binding proteins related to dystrophin. The
two skeletal muscle isof o r ms of alpha-actinin
(ACTN2 a n d ACTN3) are maj o r structural components
of the Z-line involved in anch o r ing the
actin-containing thin filaments. In humans, ACTN2
is expressed in all muscle fibers, while ACTN3 expression
is restricted to a subset of type 2 fibers (2).

Recommended Applications
WB, IHC, IP
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
IP: 1:40
Species Reactivity *
Human, Mouse, Rat
* *Cross reactivity determined by western blot only.

Products Data

A. Western blot analysis on human skeletal muscle
lysate using anti-Alpha-Actinin 2 RabMAb
(cat. # 2340-1), dilution 1:50,000

B. Immunohistochemical analysis of paraffin-embedded
human muscles using anti-Actinin 2 RabMAb (cat. #2340-1).

Specificity
A synthetic peptide corresponding to residues near
the C-terminus of human Alpha-Actinin 2 was used
as an immunogen.

贮存：

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol,
0.01% sodium azide and 0.05% BSA.