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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227178921 | Alpha-Actinin 4 | -- | 100ul | 3575元 | 现货 | 3天 |
性状: | 【产品类型】Rabbit Monoclonal Antibody 【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR4410 【用途】WB , IHC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】100 kDa |
质量标准: | 【产品介绍】Alpha-actinin is a ubiquitously expressed cytoskeletal protein found in numerous actin structures. It consists of an N-terminal actin-binding domain, a central rod domain, and a C-terminal domain; the protein functions as a homodimer to cross-link actin filaments. The rod domain determines the distance between cross-linked actin filaments and also serves as an interaction site for several cytoskeletal and signaling proteins (1). Alpha-actinin 4 is a non-muscle isoform version of alpha-actinin that is concentrated in the cytoplasm (2). It plays a role in cell motility, invasion, and metastasis of cancer cells (3). Alpha-actinin 4 is commonly expressed in filopodia, lamellipodia, stress fibers, and sites of adhesion (4). Recommended Applications Species Reactivity* Product Data Western blot analysis on (A) HeLa, (B) MCF-7, (C) C2C12, Immunohistochemical staining of paraffin-embedded Specificity |
贮存: | Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |