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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227178923 | Beta Tubulin | -- | 100ul | 3575元 | 现货 | 3天 |
性状: | 【产品类型】Rabbit Polyclonal IgG Affinity Purified 【反应特异性】Human , Mouse , Rat 【克隆 ID】polyclonal 【用途】WB , IHC , ICC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】50 kDa |
质量标准: | 【产品介绍】Microtubules are essential parts in eukaryotic cell structures, transp o r tation, a n d mitosis a n d consists mainly of 2 soluble protein subunits, alpha a n d beta tubulin. Beta-tubulin binds to alpha tubulin to f o r m tubulin heterodimer which is post-translationally modified (1). The tubulin dimer complex binds to GTP a n d assembles onto the positive ends of microtubules. After inc o r p o r ation into the microtubules, bound GTP is hydrolyzed by beta tubulin. The stability of the dimer in the microtubules is depended on presence of beta tubulin, where dimer with GTP bound beta-tubulin is stable to microtubule inc o r p o r ation (2). Mutation on beta-tubulin has been linked to anti-cancer drug resistance in lung cancers (3). Recommended Applications A. Western blot analysis on HeLa cell lysate using B.Immunofluorescent staining of HeLa cells using C. Immunohistochemical analysis of paraffin-embedded Specificity |
贮存: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |