|
货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227178925 | Beta-Tubulin | -- | 100ul | 3575元 | 现货 | 3天 |
性状: | 【产品类型】Rabbit Monoclonal Antibody 【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR1330 【用途】WB , IHC , ICC , FC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】50 kDa |
质量标准: | 【产品介绍】Microtubules are essential parts in eukaryotic cell structures, transportation, and mitosis and consists mainly of 2 soluble protein subunits, alpha and beta tubulin. Beta-tubulin binds to alpha tubulin to form tubulin heterodimer which is posttranslationally modified (1). The tubulin dimer complex binds to GTP and assembles onto the positive ends of microtubules. After incorporation into the microtubules, bound GTP is hydrolyzed by beta tubulin. The stability of the dimer in the microtubules is depended on presence of beta tubulin, where dimer with GTP bound beta-tubulin is stable to microtubule incorporation (2). Mutation on beta-tubulin has been linked to anti-cancer drug resistance in lung cancers (3). Recommended Applications Species Reactivity* Product Data Western blot analysis on (A) MCF-7, (B) Jurkat, (C) Immunohistochemical analysis of paraffin-embedded Immunohistochemical analysis of paraffin-embedded Immunofluorescent staining of HeLa cells using Specificity |
贮存: | Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |