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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227178926 | GAPDH | -- | 100ul | 3575元 | 现货 | 3天 |
性状: | 【产品类型】Rabbit Monoclonal IgG 【反应特异性】Human , Mouse , Rat 【克隆ID 】 EPR1977Y 【用途】 WB,IHC,ICC,IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】 35 kDa的 |
质量标准: | 【产品介绍】Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was considered a classical glycolytic protein involved exclusively in cytosolic energy production. However, recent evidence suggests that it is a multifunctional protein displaying diverse activities distinct from its conventional metabolic role. These new roles f o r GAPDH may be dependent on its subcellular localization, oligomeric state o r on the proliferative state of the cell. Results suggest that human cells contain significant intracellular levels of enzymatically inactive GAPDH which is age- independent. The possibility is considered that the functional diversity of GAPDH may be mediated either by posttranslational alteration o r by subcellular protein:protein a n d / o r protein:nucleic acid interactions (1). GAPDH mRNA levels, protein, a n d enzymatic activity have been shown to increase increase in 3T3 cells after exposure to physiological concentrations of insulin (2). Recommended Applications A. Western blot analysis on (A) NIH/3T3 or (B) HeLa B. Immunohistochemical analysis of paraffin-embedded |
贮存: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |