hnRNP C2_珈得尔化学试剂

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hnRNP C2

HNRNPC

别名：	HNRNPC antibody, C1 antibody, C2 antibody, HNRNP antibody, HNRPC antibody, MGC104306 antibody, MGC105117 antibody, MGC117353 antibody, MGC131677 antibody, SNRPC antibody, Heterogeneous nuclear ribonucleoproteins C1/C2 antibody, antibody
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227178962	hnRNP C2	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPNCIR152
【用途】WB , IHC , ICC , FC , IP 【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】42kDa

质量标准：

【产品介绍】Heterogeneous nuclear
ribonucleoproteins (hnRNPs) are predominantly
nuclear RNA-binding proteins that form complexes with
RNA polymerase II transcripts. These proteins function in
a variety of cellular activities, ranging from
transcription and pre-mRNA processing in the nucleus
to cytoplasmic mRNA translation and turnover (1). hnRNP
C2 is one of the most abundant proteins in the nucleus,
and shown to have roles in cellular differentiation
and proliferation (2). A novel nuclear export is
activated by the ROCK signaling pathway to exclude hnRNP
C2 from the nucleus, by which the compartmentalization
of specific hnRNP components is disturbed in apoptotic
cells (3). Overexpression of hnRNP C2 in
hepatocellular carcinoma (HCC) tissues has been reported
in 70 HCC samples, suggesting its potential as a
protein tumor marker (4).

Recommended Applications
WB, IHC, ICC, IP, FC
Applications and Recommended Dilution Factors
WB: 1:10,000 - 50,000
IHC: 1:250 - 500
ICC: 1:250 - 500
IP: 1:10 - 100
FC: 1:10 - 100
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) HeLa, (B) MCF-7, (C) HepG2,
(D) K562, and (E) 293T cell lysates using anti-hnRNP
C2 RabMAb (cat. #5449-1).

Immunohistochemical analysis of paraffin-embedded
human kidney tissue using anti-hnRNP C2 RabMAb
(cat. #5449-1).

Immunohistochemical analysis of paraffin-embedded
human thyroid carcinoma tissue using anti-hnRNP C2
RabMAb (cat. #5449-1).

Specificity
A synthetic peptide corresponding to residues in human
hnRNP C2 was used as an immunogen. This antibody is
specific to isoform C2.

This antibody was developed as part of a
collaboration between Epitomics, the National
Cancer Institute's Center for Cancer Research and the lab
of Mirit Aladjem.

贮存：

Store at -20° C. Buffer: Antibody buffer, sodium
azide, glycerol, and BSA. Stable for 12 months from date
of receipt.