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| 货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
| JD1227179014 | JAM1 (N-term) | -- | 100ul | 0元 | 现货 | 3天 |
| 性状： | 【产品类型】Rabbit Monoclonal IgG 【反应特异性】Human , Mouse , Rat 【克隆 ID】EP1042Y 【用途】WB , IHC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】33 kDa |
| 质量标准： | 【产品介绍】Junctional Adhesion Molecules (JAMs) are components a n d regulat o r s of the well- characterized epithelial a n d endothelial tight junction. JAM is s e l e c tively concentrated at intercellular junctions of endothelial a n d epithelial cells of different o r igins. Microscopy shows that JAM codistributes with tight junction components at the apical region of the intercellular cleft. A mAb directed to JAM (BV11) was found to inhibit spontaneous a n d chemokine-induced monocyte transmigration through an endothelial cell monolayer in vitro. Systemic treatment of mice with BV11 mAb blocked monocyte infiltration upon chemokine administration in subcutaneous air pouches (1). The human protein shares a highly conserved structure a n d sequence with the murine protein. However it is distinct in that it is constitutively expressed on circulating neutrophils, monocytes, platelets a n d lymphocyte subsets (2). WB: 1:2000 A. Western blot analysis on HeLa cell lysate using B. Immunohistochemical staining of paraffin-embedded |
