JNK2 (MAPK9)_珈得尔化学试剂

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JNK2 (MAPK9)

别名：	MAPK9 antibody, JNK-55 antibody, JNK2 antibody, JNK2A antibody, JNK2ALPHA antibody, JNK2B antibody, JNK2BETA antibody, PRKM9 antibody, SAPK antibody, p54a antibody, p54aSAPK antibody, Mitogen-activated protein kinase 9 antibody, JNK-55 antibody, Stress-ac
Cas号：	--	M D L：	--
分子式：	--	分子量：	--

货号	品名	规格	包装	单价	货期	库存
JD1227179018	JNK2 (MAPK9)	--	100ul	0元	现货	3天

物流提示：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。

性状：

【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EP1595Y
【用途】WB , IHC , ICC , FC , IP
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】54/46kDa

质量标准：

【产品介绍】JNK protein kinases are distantly related
to mitogen-activated protein kinases (ERKs) and
are activated by dual phosphorylation on Tyr and Thr.
The JNK protein kinase group includes the 46-kDa
isoform JNK1 and the 55-kDa protein kinase JNK2.
The activities of both JNK isoforms are markedly
increased by exposure of cells to UV radiation (1).
JNK becomes activated in vivo in response
to pro-inflammatory cytokines or cellular stresses. Its
full activation requires the phosphorylation of a
threonine and a tyrosine residue in a Thr-Pro-Tyr
motif, which can be catalysed by the protein kinases
mitogen-activated protein kinase kinase MKK4 and MKK7
(2). JNK2 functions in a cell-type-specific and
stimulus-dependent manner, being required for apoptosis
of immature thymocytes induced by anti-CD3 antibody but
not for apoptosis induced by anti-Fas antibody, UVC
or dexamethasone. JNK2 is not required for
activation-induced cell death of mature T cells (3).

Recommended Applications
WB, IHC, ICC, IP, FC
Applications and Recommended Dilution Factors
WB: 1:2,000 - 50,000
IHC: 1:100 - 250
ICC: 1:100 - 250
IP: 1:100
FC: 1:40
Species Reactivity *
Human, Mouse, Rat
*For Mouse, this antibody is recommended for WB only
Rat cross reactivity tested by western blot only

Products Data

A. Western blot analysis on HeLa cell lysate using
anti-JNK2 RabMAb (cat. # 2037-1), dilution 1:50,000.

B. Immunohistochemical staining of paraffin-embedded
human breast carcinoma using anti-JNK2 RabMAb (cat. #2037-1).

Specificity
A synthetic peptide corresponding to residues near
the C-terminus of human JNK2 was used as an immunogen.

贮存：

Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt.