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货号 | 品名 | 规格 | 包装 | 单价 | 货期 | 库存 |
JD1227179043 | LIN28A DyLight® 594 | -- | 100ul | 0元 | 现货 | 3天 |
性状: | 【产品类型】Rabbit Monoclonal Antibody 【反应特异性】Human 【克隆 ID】EPR4640 【用途】ICC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】26kDa |
质量标准: | 【产品介绍】LIN28A, a promoter of pluripotency, is a developmentally regulated RNA binding protein, which selectively blocks the processing of pri-let-7 miRNAs in embryonic cells (1,2). One of the let-7 family members, let-7g targets and represses LIN28 through four 3'-UTR binding sites. It has been reported that LIN28/let-7 pair has the potential to act as a 'toggle switch' that balances the decision to maintain pluripotency vs. differentiation (3). LIN28 was identified as a negative regulator of miRNA biogenesis and suggested that it may play a central role in blocking miRNA-mediated differentiation in stem cells and in certain cancers (1). Recommended Applications Products Data Immunofluorescent analysis of NCCIT cells using Specificity |
贮存: | Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt. |