Recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed) 是肿瘤坏死因子超家族的一员，在外周 B 细胞内稳态中具有重要作用。
Synonyms
rHuBAFF/TNFSF13B; BLYS; TALL1; THANK; ZTNF4; TALL-1; TNFSF20 ; 重组人 B 细胞激活因子/TNFSF13B (CHO 细胞表达)
Species
HumanSource
CHO Accession
Q9Y275 Gene ID
10673 Molecular Weight
Approximately 17 kDa AA Sequence
AVQGPEETVT QDCLQLIADS ETPTIQKGSY TFVPWLLSFK RGSALEEKEN KILVKETGYF FIYGQVLYTD KTYAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PRENAQISLD GDVTFFGALK LL Biological Activity
The ED50 is <20 ng/mL as measured by human RPMI 8226 cells, corresponding to a specific activity of >5.0 × 104 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed) (rHuBAFF/TNFSF13B) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability
Lyophilized recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed) (rHuBAFF/TNFSF13B) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
B-cell activating factor (BAFF), a member of the tumor necrosis factor (TNF) superfamily, is secreted by various myeloid cells such as macrophages, dendritic cells, and neutrophils. BAFF is a potent survival factor for B cells and plays an essential role in peripheral B-cell homeostasis[1]. |
