Recombinant Human Bone Morphogenetic Protein 2 是一种有效的骨形成蛋白，能够促进骨折愈合，缩短整合时间
Synonyms
rHuBMP-2; BMP2A; BMP-2A; BMP2 ; 重组人骨形态发生蛋白 2
Species
HumanSource
E. coli Accession
P12643 Gene ID
650 Molecular Weight
Approximately 26 kDa AA Sequence
MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR Biological Activity
The ED50 is 70-200 ng/mL as measured by ATDC-5 cells. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against 50 mM acetic acid. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Bone Morphogenetic Protein 2 (rHuBMP-2) to 100 µg/mL using 20 mM AcOH or diluted with 5 mM HCl. Storage & Stability
Lyophilized recombinant Human Bone Morphogenetic Protein 2 (rHuBMP-2) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Recombinant Human Bone Morphogenetic Protein 2 is a bone morphogenetic protein, effective in bone fracture healing, and shortens the consolidation phase. Recombinant Human Bone Morphogenetic Protein 2 is a therapeutic option in the treatment of several congenital and acquired craniofacial defects[1]. Recombinant Human Bone Morphogenetic Protein 2 (rhBMP-2) products have been approved by FDA and the European Medicines Agency and has some clinical success for bone repair[2] |
