Recombinant Human Fibroblast Growth Factor 4 是一种成纤维细胞生长因子 (FGF)，能够高效地转化 3T3 细胞，刺激内皮细胞增殖，迁移和蛋白酶的产生，具有心血管生成的活性。
Synonyms
rHuFGF-4; HBGF-4; HST; HST-1; HSTF1 ; 重组人成纤维细胞生长因子 4
Species
HumanSource
E. coli Accession
P08620 Gene ID
2249 Molecular Weight
Approximately 19.4 kDa AA Sequence
MAPTAPNGTL EAELERRWES LVALSLARLP VAAQPKEAAV QSGAGDYLLG IKRLRRLYCN VGIGFHLQAL PDGRIGGAHA DTRDSLLELS PVERGVVSIF GVASRFFVAM SSKGKLYGSP FFTDECTFKE ILLPNNYNAY ESYKYPGMFI ALSKNGKTKK GNRVSPTMKV THFLPRL Biological Activity
The ED50 is <0.5 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >2.0 × 106 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against 50 mM HEPES, 750 mM NaCl, pH 7.5. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Fibroblast Growth Factor 4 (rHuFGF-4) to 100 µg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Human Fibroblast Growth Factor 4 (rHuFGF-4) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Fibroblast Growth Factor 4 (EGF 4) is a member of the FGF family that transforms 3T3 cells with high efficiency, stimulates endothelial cell proliferation, migration, and protease production, and shows angiogenic activity[1]. |
