Recombinant Human Interferon-beta1b 是一种细胞因子，具有免疫调节作用。
Synonyms
rHuIFN-β; IFNB ; 重组人干扰素-β1b
Species
HumanSource
HEK 293 Accession
P01574 Gene ID
3456 Molecular Weight
Approximately 23 kDa AA Sequence
MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN Biological Activity
The ED50 is <0.1 ng/mL as measured by TF-1 cells. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Interferon-beta (HEK293-expressed) (rHuIFN-β) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability
Lyophilized recombinant Human Interferon-beta (HEK293-expressed) (rHuIFN-β) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Interferon-beta is a cytokine with immunomodulatory properties, and has therapeutic potential for the treatment of ischemic stroke[1]. Interferon-beta (IFN-β) suppresses the production of IFN-γ and induces IL-10, whereas the production of IL-4 is not altered[2]. |
