Recombinant Human Interleukin-16, 130a.a. 是一种来源于 E. coli 的含有 130 个氨基酸的促炎细胞因子。
Synonyms
rHuIL-16; Lymphocyte chemoattractant factor; LCF
Species
HumanSource
E. coli Accession
Q14005 Gene ID
3603 Molecular Weight
Approximately 13,400 Da AA Sequence
MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against 20 mM acetic buffer, pH 5.0, 150 mM NaCl and 0.5 mM DTT. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Interleukin-16, 130a.a. (rHuIL-16, 130a.a.) to 100 µg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Human Interleukin-16, 130a.a. (rHuIL-16, 130a.a.) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Recombinant Human IL-16 produced in E. coli is a single, non-glycosylated polypeptide chain containing 130 amino acids. Interleukin-16, a proinflammatory cytokine produced in CD8+ lymphocytes, is synthesized as a precursor protein (pro-IL-16). It is postulated that the C-terminal region of pro-IL-16 is cleaved, releasing bioactive IL-16. IL-16 is produced and secreted predominantly by CD8+ T lymphocytes, and it exerts chemoattractant, growth factor, and other activities on lymphocytes, monocytes, and eosinophils by interaction with CD4[1]. |
