Recombinant Mouse Interleukin-9 是 TH2 细胞因子家族的成员,是粘膜免疫和特应性哮喘敏感性的必需因子。 Synonyms rMuIL-9; Cytokine P40; T-cell Growth Factor P40 Species MouseSource CHO Accession P15247 Gene ID 16198 Molecular Weight Approximately 14 kDa AA Sequence QRCSTTWGIR DTNYLIENKL DDPPSKCSCS GNVTSCLCLS VPTDDCTTPC YREGLLQLTN ATQKSRLLPV FHRVKRIVEV LKNITCPSFS CEKPCNQTMA GNTLSFLKSL LGTFQKTEMQ RQKSRP Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Murine Interleukin-9 (rMuIL-9) to 100 µg/mL using ddH2O. Storage & Stability Lyophilized recombinant Murine Interleukin-9 (rMuIL-9) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Interleukin 9 (IL-9) is cytokine produced by a subgroup of helper T cells, known as Th2 cells. IL-9 signals through its receptor IL-9R to induce cell proliferation and survival. Genetically, IL-9 has been identified as a gene associated with asthma.Human interleukin-9 (IL-9) was originally identified and cloned based on its stimulatory effect on proliferation of human myeloid cell line, M07e. IL-9 synergized with Steel factor, the ligand for the c-kit product, to stimulate M07e cell proliferation[1] |