Recombinant Mouse Adiponectin 能够抑制内皮炎症反应和血管平滑肌细胞增值，还能抑制巨噬细胞向泡沫细胞转化。
Synonyms
rMuAdiponectin; Acrp-30; GBP-28; Apm-1; Acrp 30; Acrp30 ; 重组小鼠脂联素
Species
MouseSource
E. coli Accession
Q60994 Gene ID
11450 Molecular Weight
Approximately 24.6 kDa AA Sequence
VTTTEELAPA LVPPPKGTCA GWMAGIPGHP GHNGTPGRDG RDGTPGEKGE KGDAGLLGPK GETGDVGMTG AEGPRGFPGT PGRKGEPGEA AYVYRSAFSV GLETRVTVPN VPIRFTKIFY NQQNHYDGST GKFYCNIPGL YYFSYHITVY MKDVKVSLFK KDKAVLFTYD QYQEKNVDQA SGSVLLHLEV GDQVWLQVYG DGDHNGLYAD NVNDSTFTGF LLYHDTN Biological Activity
The ED50 is <5 μg/mL as measured by M1 cells, corresponding to a specific activity of >2.0 × 102 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Mouse Adiponectin (rMuAdiponectin) to 100 μg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Mouse Adiponectin (rMuAdiponectin) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Recombinant Mouse Adiponectin promotes adipocyte differentiation, fatty acid catabolism, and insulin sensitivity, and is negatively correlated with obesity, type 2 diabetes, and atherogenesis. Adiponectin is also an anti-inflammatory agent; it exerts pro-inflammatory effects in nonmetabolic disorders such as rheumatoid arthritis and inflammatory bowel disease. |
