Recombinant Rat Beta Defensin-1是一种抗菌肽，能够保护上皮表面，包括皮肤，胃肠道和呼吸道
Synonyms
rRtBD-1; HBD1; DEFB1 ; 重组大鼠 β-防御素-1
Species
RatSource
E. coli Accession
O89117 Gene ID
83687 Molecular Weight
Approximately 4.1 kDa AA Sequence
DQYRCLQNGG FCLRSSCPSH TKLQGTCKPD KPNCCRS Biological Activity
Full biological activity determined by a chemotaxis bioassay using CD34+ dendritic cells is in a concentration range of 100-1000 ng/ml. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against 20 mM PBS, 500 mM NaCl, pH 7.0. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Rat Beta Defensin-1 (rRtBD-1) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability
Lyophilized recombinant Rat Beta Defensin-1 (rRtBD-1) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Beta Defensin-1 displays potent microcidal properties, and also plays a part in other aspects of innate and adaptive immunity[1]. Rat Beta Defensin-1 reduction may be in part responsible for the high incidence of urinary tract infections in diabetes mellitus[2]. |
