Recombinant Mouse CCL6，是一种CC型趋化因子，与慢性炎症中的巨噬细胞浸润有关。
Synonyms
rMuCCL6; C-C motif chemokine 6; Scya6; C10 ; 重组小鼠 CC 趋化因子6 (CCL6)
Species
MouseSource
E. coli Accession
P27784 Gene ID
20305 Molecular Weight
Approximately 10.7 kDa AA Sequence
GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA Biological Activity
Full biological activity determined by a chemotaxis bioassay using human CCR1 transfected murine BaF3 cells is in a concentration range of 10-100 ng/ml. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against 20 mM Tris, pH 8.0, 500 mM NaCl. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Mouse CCL6 (rMuCCL6) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability
Lyophilized recombinant Mouse CCL6 (rMuCCL6) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
C10/CCL6 shares significant homology with other chemokines, including human MIP-1γ, CC chemokine F-18 (CCF-18), hemofiltrate CC chemokine (HCC-1), and HCC-2[1]. CCL6 is present in a variety of chronic inflammatory disorders including experimental demyelinating diseases, allergic airway inflammation, bleomycin-induced lung fibrosis and chronic peritonitis. CCL6 also can be used as a monocyte chemoattractant in a murine acute peritonitis[2]. |
