Recombinant Mouse Fibroblast Growth Factor-10 是一种旁分泌信号分子，参与肺、皮肤、耳、唾液腺等多个器官形态分支的发生。
Synonyms
rMuFGF-10; Keratinocyte growth factor-2; Fgf10 ; 重组小鼠成纤维细胞生长因子-10
Species
MouseSource
E. coli Accession
O35565 Gene ID
14165 Molecular Weight
Approximately 17 kDa AA Sequence
SSAGRHVRSY NHLQGDVRWR RLFSFTKYFL TIEKNGKVSG TKNEDCPYSV LEITSVEIGV VAVKAINSNY YLAMNKKGKL YGSKEFNNDC KLKERIEENG YNTYASFNWQ HNGRQMYVAL NGKGAPRRGQ KTRRKNTSAH FLPMTIQT Biological Activity
The ED50 is <10 ng/mL as measured by 4MBr-5 cells, corresponding to a specific activity of >1.0 × 105 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Mouse Fibroblast Growth Factor-10 (rMuFGF-10) to 100 μg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Mouse Fibroblast Growth Factor-10 (rMuFGF-10) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Mature mouse Fibroblast Growth Factor-10 (FGF10) shares 94% and 100% amino acid sequence identity with human and rat FGF10, respectively. The mitogenic and chemotactic properties of FGF10 are critical in many tissues during embryogenesis. FGF10 induces signaling through FGF R2 (IIIb) also contributes to the progression of pancreatic cancer[1]. FGF10 is a paracrine signaling molecule and is involved in the branching of morphogenesis in multiple organs such as the lungs, skin, ear and salivary glands[2]. |
