Recombinant Mouse GRO alpha/CXCL1 (CHO expressed) 在炎症、血管生成、肿瘤发生和伤口愈合中起重要作用。
Synonyms
rMuGRO-α/CXCL1; Growth-regulated alpha protein; C-X-C motif chemokine 1; KC; HSF ; 重组小鼠 CXC 趋化因子1 (CHO 细胞表达)
Species
MouseSource
CHO Accession
P12850 Gene ID
14825 Molecular Weight
5-7 kDa AA Sequence
APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK Biological Activity
The ED50 is <10 ng/mL as measured by HUVEC cells. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Mouse GRO alpha/CXCL1 (CHO-expressed) (rMuGRO-α/CXCL1) to 100 μg/mL using ddH2O or PBS. Storage & Stability
Lyophilized recombinant Mouse GRO alpha/CXCL1 (CHO-expressed) (rMuGRO-α/CXCL1) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
CXCL1 plays a major role in inflammation, angiogenesis, tumorigenesis, and wound healing. CXCL1 is shown to be up-regulated in melanoma cells, and it is involved in pathogenesis of melanoma[1]. |
